Sometimes doctors need to clean out the area under the foreskin and instruct the man about good hygiene. Health Information A-Z Our index of medical information authored by professionals Community Join the discussion in our forums Medicine directory Drug treatments, dosage instructions and side effects Medical Professionals Information for medical professionals Symptom Checker Assess your symptoms online with our free symptom checker. What is Inflammation of the Penis and Prepuce? I have tested like 10 times, made all possible tests there are available - but all negative except HPV. A number of problems can cause painful intercourse. This may be all you need to stop the inflammation, swelling, itching, and discharge. A fractured penis can be caused by too much force on the penis during sexual intercourse or masturbation.